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The Science & Faith Podcast - James Tour & John Sanford: Genetic Entropy & Genome Degeneration


Video from Dr. James Tour


"In this podcast, Dr. James Tour and Dr. John Sanford discuss science and faith, including Dr. Sanford's challenge against the idea of natural selection benefiting the fitness of living organisms, coming as a direct result of his research on genomes showing the fitness of biological systems are degenerating due to the accumulation of harmful mutations. Dr. Sanford also introduces Biblical data that coincidentally matches the degeneration curve and biological decay. Questions from the audience conclude the talk." from video introduction.


"And lest I should be exalted above measure through the abundance of the revelations, there was given to me a thorn in the flesh, the messenger of Satan to buffet me, lest I should be exalted above measure" II Cor. 12:7.


Cancer & Genetic Entropy

I like many of you are a cancer survivor, of four cancers in my case. I have no doubt that my sins and the sins of those that lived before me have produced a debility in my body i.e. cancer from that sin!

We are like the 20th copy on a copy machine, faint, gray and weak, hard to see or read. Yet God is good and someday we will be in our resurrection bodies with our Lord! - Andy


"The doctrine of evolution tends to magnify the competitive aspects of nature and to minimize the cooperative aspects. "Nature red in tooth and claw" is indeed the theme of many evolutionary books. However, the living world around us has many examples of cooperative or symbiotic behavior at many different levels. We need look no further than our own bodies for some of the most marvelous instances of cooperative activity in all of creation. The processes of breathing, digestion, muscular contraction and coordination, nutrient transport, and their direction by the neural and endocrine systems, have shown an amazing sophistication of cooperation through molecular biologic research. The discovery of such intricate cooperation at the cellular level should not surprise Christians, as the Bible speaks of the human body as being a symbol of the great congregation of God's people, or the "body of Christ."

Cancer upsets this normal state of harmonious, cooperative cellular function. For childhood growth and adult maintenance to occur, cells must divide constantly in the human body. However, cancer cells are characterized by their uncontrolled growth—they do not respond to signals to stop the division process, but instead continue on and on. In the body, cancer cells invade and kill their neighbor cells. They may cannibalize each other. They often outgrow their own blood supply, thus killing even themselves. In artificial cell culture, cancer cells will show this trait in a slightly different way, for they will grow until they pile up and suffocate each other. Normal cells in culture, on the other hand, will grow on the bottom of the bottle until they form a continuous single cell layer. Then, sensing the presence of a neighbor, they will chemically signal each other to quit replicating. Normal human cells will respect boundaries and not harm their neighbors, whereas cancer cells will aggressively invade, suffocate, and destroy their neighbors..." from the article: Cancer & the Curse


"Cancer is a genetic disease—that is, cancer is caused by certain changes to genes that control the way our cells function, especially how they grow and divide.

Genes carry the instructions to make proteins, which do much of the work in our cells. Certain gene changes can cause cells to evade normal growth controls and become cancer. For example, some cancer-causing gene changes increase production of a protein that makes cells grow. Others result in the production of a misshapen, and therefore nonfunctional, form of a protein that normally repairs cellular damage.

Genetic changes that promote cancer can be inherited from our parents if the changes are present in germ cells, which are the reproductive cells of the body (eggs and sperm). Such changes, called germline changes, are found in every cell of the offspring..." from the article: The Genetics of Cancer


"What is Genetic Entropy? It is the genetic degeneration of living things. Genetic entropy is the systematic breakdown of the internal biological information systems that make life alive. Genetic entropy results from genetic mutations, which are typographical errors in the programming of life (life’s instruction manuals). Mutations systematically erode the information that encodes life’s many essential functions. Biological information consists of a large set of specifications, and random mutations systematically scramble these specifications – gradually but relentlessly destroying the programming instructions essential to life... from the website: Genetic Entropy


"Answering The Critics

Genetic Entropy: Fact or Fiction – Part 1 by Steve Hudgik

Genetic entropy provides overwhelming scientific evidence that evolution never happened. If genetic entropy is true (and it is), evolution is impossible. It makes sense that science and the Bible would agree on this. The Bible leaves no room for evolution, and we'd expect to see that in nature... and we do.

As a starting point, we need to define genetic entropy. What are we talking about when we use the term, “genetic entropy?” Dr. John Sanford is the geneticist who first studied this. Here is how he defines genetic entropy:

“The genetic degeneration of living things. “Genetic entropy is the systematic breakdown of the internal biological information systems that make life alive. Genetic entropy results from genetic mutations, which are typographical errors in the programming of life (life’s instruction manuals). Mutations systematically erode the information that encodes life’s many essential functions. Biological information consists of a large set of specifications, and random mutations systematically scramble these specifications – gradually but relentlessly destroying the programming instructions essential to life.” - https://www.geneticentropy.org/whats-genetic-entropy

What this means is that with each generation our genome (our genetic information) is degrading. Unlike the claim of evolution that we are improving, genetic entropy states that we are de-evolving. We are losing information from our genome with each generation... mutations are accumulating, and we are heading toward extinction.”.." from the article: Answering The Critics Genetic Entropy: Fact or Fiction – Part 1


"Abstract

Many types of cancer are intrinsically linked to the process of aging. Aging, from the perspective of the second law of thermodynamics, can be viewed as associated with the inevitable and natural increase in informational entropy of the genome. The molecular biologic basis of increasing genetic informational entropy is the inherent and variable instability of different regions of genome. Colon cancer cells have been shown to have characteristic acquired genetic abnormalities, most commonly, deletions in presumed tumor suppressor genes. Age-specific colon cancer mortality rates in the US from 1958 to 1988 were subjected to longitudinal Gompertzian analysis, a method that may identify and distinguish among genetic, environmental and competitive influences upon mortality. The Strehler-Mildvan modification of the Gompertz relationship between aging and mortality can be used to determine a relative measure of the rate of increase in informational entropy (a reflection of genetic instability) for those genetic factors that are involved in the pathogenesis of colon cancer..." from the article: Aging, genomic entropy and carcinogenesis: implications derived from longitudinal age-specific colon cancer mortality rate dynamics



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